diff --git a/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp b/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
index 283c4fbbb7c..9884ed15b8a 100644
--- a/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
+++ b/compiler/rustc_llvm/llvm-wrapper/PassWrapper.cpp
@@ -1607,8 +1607,13 @@ extern "C" void LLVMRustComputeLTOCacheKey(RustStringRef KeyOut,
   const auto &ExportList = Data->ExportLists.lookup(ModId);
   const auto &ResolvedODR = Data->ResolvedODR.lookup(ModId);
   const auto &DefinedGlobals = Data->ModuleToDefinedGVSummaries.lookup(ModId);
+#if LLVM_VERSION_GE(20, 0)
+  DenseSet<GlobalValue::GUID> CfiFunctionDefs;
+  DenseSet<GlobalValue::GUID> CfiFunctionDecls;
+#else
   std::set<GlobalValue::GUID> CfiFunctionDefs;
   std::set<GlobalValue::GUID> CfiFunctionDecls;
+#endif
 
   // Based on the 'InProcessThinBackend' constructor in LLVM
   for (auto &Name : Data->Index.cfiFunctionDefs())
@@ -1618,9 +1623,15 @@ extern "C" void LLVMRustComputeLTOCacheKey(RustStringRef KeyOut,
     CfiFunctionDecls.insert(
         GlobalValue::getGUID(GlobalValue::dropLLVMManglingEscape(Name)));
 
+#if LLVM_VERSION_GE(20, 0)
+  Key = llvm::computeLTOCacheKey(conf, Data->Index, ModId, ImportList,
+                                 ExportList, ResolvedODR, DefinedGlobals,
+                                 CfiFunctionDefs, CfiFunctionDecls);
+#else
   llvm::computeLTOCacheKey(Key, conf, Data->Index, ModId, ImportList,
                            ExportList, ResolvedODR, DefinedGlobals,
                            CfiFunctionDefs, CfiFunctionDecls);
+#endif
 
   LLVMRustStringWriteImpl(KeyOut, Key.c_str(), Key.size());
 }