2013-04-19 21:21:53 -05:00
|
|
|
// xfail-test
|
|
|
|
|
2013-04-17 20:59:54 -05:00
|
|
|
extern mod std;
|
|
|
|
|
|
|
|
use core::cast::transmute;
|
|
|
|
use core::i32::range;
|
|
|
|
use core::libc::{STDIN_FILENO, c_int, fdopen, fgets, fileno, fopen, fstat};
|
|
|
|
use core::libc::{stat, strlen};
|
|
|
|
use core::ptr::null;
|
|
|
|
use core::unstable::intrinsics::init;
|
|
|
|
use core::vec::{reverse, slice};
|
|
|
|
use std::sort::quick_sort3;
|
|
|
|
|
|
|
|
static LINE_LEN: uint = 80;
|
|
|
|
static TABLE: [u8, ..4] = [ 'A' as u8, 'C' as u8, 'G' as u8, 'T' as u8 ];
|
|
|
|
static TABLE_SIZE: uint = 2 << 16;
|
|
|
|
|
|
|
|
static OCCURRENCES: [&'static str, ..5] = [
|
|
|
|
"GGT",
|
|
|
|
"GGTA",
|
|
|
|
"GGTATT",
|
|
|
|
"GGTATTTTAATT",
|
|
|
|
"GGTATTTTAATTTATAGT",
|
|
|
|
];
|
|
|
|
|
|
|
|
// Code implementation
|
|
|
|
|
|
|
|
#[deriving(Eq, Ord)]
|
|
|
|
struct Code(u64);
|
|
|
|
|
|
|
|
impl Code {
|
|
|
|
fn hash(&self) -> u64 {
|
|
|
|
**self
|
|
|
|
}
|
|
|
|
|
|
|
|
#[inline(always)]
|
|
|
|
fn push_char(&self, c: u8) -> Code {
|
|
|
|
Code((**self << 2) + (pack_symbol(c) as u64))
|
|
|
|
}
|
|
|
|
|
|
|
|
fn rotate(&self, c: u8, frame: i32) -> Code {
|
|
|
|
Code(*self.push_char(c) & ((1u64 << (2 * (frame as u64))) - 1))
|
|
|
|
}
|
|
|
|
|
|
|
|
fn pack(string: &str) -> Code {
|
|
|
|
let mut code = Code(0u64);
|
|
|
|
for uint::range(0, string.len()) |i| {
|
|
|
|
code = code.push_char(string[i]);
|
|
|
|
}
|
|
|
|
code
|
|
|
|
}
|
|
|
|
|
|
|
|
// XXX: Inefficient.
|
|
|
|
fn unpack(&self, frame: i32) -> ~str {
|
|
|
|
let mut key = **self;
|
|
|
|
let mut result = ~[];
|
|
|
|
for (frame as uint).times {
|
|
|
|
result.push(unpack_symbol((key as u8) & 3));
|
|
|
|
key >>= 2;
|
|
|
|
}
|
|
|
|
|
|
|
|
reverse(result);
|
|
|
|
str::from_bytes(result)
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
// Hash table implementation
|
|
|
|
|
|
|
|
trait TableCallback {
|
|
|
|
fn f(&self, entry: &mut Entry);
|
|
|
|
}
|
|
|
|
|
|
|
|
struct BumpCallback;
|
|
|
|
|
|
|
|
impl TableCallback for BumpCallback {
|
|
|
|
fn f(&self, entry: &mut Entry) {
|
|
|
|
entry.count += 1;
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
struct PrintCallback(&'static str);
|
|
|
|
|
|
|
|
impl TableCallback for PrintCallback {
|
|
|
|
fn f(&self, entry: &mut Entry) {
|
|
|
|
println(fmt!("%d\t%s", entry.count as int, **self));
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
struct Entry {
|
|
|
|
code: Code,
|
|
|
|
count: i32,
|
|
|
|
next: Option<~Entry>,
|
|
|
|
}
|
|
|
|
|
|
|
|
struct Table {
|
|
|
|
count: i32,
|
|
|
|
items: [Option<~Entry>, ..TABLE_SIZE]
|
|
|
|
}
|
|
|
|
|
|
|
|
impl Table {
|
|
|
|
fn new() -> Table {
|
|
|
|
Table {
|
|
|
|
count: 0,
|
|
|
|
items: [ None, ..TABLE_SIZE ],
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
fn search_remainder<C:TableCallback>(item: &mut Entry, key: Code, c: C) {
|
|
|
|
match item.next {
|
|
|
|
None => {
|
|
|
|
let mut entry = ~Entry {
|
|
|
|
code: key,
|
|
|
|
count: 0,
|
|
|
|
next: None,
|
|
|
|
};
|
|
|
|
c.f(entry);
|
|
|
|
item.next = Some(entry);
|
|
|
|
}
|
|
|
|
Some(ref mut entry) => {
|
|
|
|
if entry.code == key {
|
|
|
|
c.f(*entry);
|
|
|
|
return;
|
|
|
|
}
|
|
|
|
|
|
|
|
Table::search_remainder(*entry, key, c)
|
|
|
|
}
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
fn lookup<C:TableCallback>(&mut self, key: Code, c: C) {
|
|
|
|
let index = *key % (TABLE_SIZE as u64);
|
|
|
|
|
|
|
|
{
|
|
|
|
if self.items[index].is_none() {
|
|
|
|
let mut entry = ~Entry {
|
|
|
|
code: key,
|
|
|
|
count: 0,
|
|
|
|
next: None,
|
|
|
|
};
|
|
|
|
c.f(entry);
|
|
|
|
self.items[index] = Some(entry);
|
|
|
|
return;
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
{
|
|
|
|
let mut entry = &mut *self.items[index].get_mut_ref();
|
|
|
|
if entry.code == key {
|
|
|
|
c.f(*entry);
|
|
|
|
return;
|
|
|
|
}
|
|
|
|
|
|
|
|
Table::search_remainder(*entry, key, c)
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
fn each(&self, f: &fn(entry: &Entry) -> bool) {
|
|
|
|
for self.items.each |item| {
|
|
|
|
match *item {
|
|
|
|
None => {}
|
|
|
|
Some(ref item) => {
|
|
|
|
let mut item: &Entry = *item;
|
|
|
|
loop {
|
|
|
|
if !f(item) {
|
|
|
|
return;
|
|
|
|
}
|
|
|
|
|
|
|
|
match item.next {
|
|
|
|
None => break,
|
|
|
|
Some(ref next_item) => item = &**next_item,
|
|
|
|
}
|
|
|
|
}
|
|
|
|
}
|
|
|
|
};
|
|
|
|
}
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
// Main program
|
|
|
|
|
|
|
|
fn pack_symbol(c: u8) -> u8 {
|
|
|
|
match c {
|
|
|
|
'a' as u8 | 'A' as u8 => 0,
|
|
|
|
'c' as u8 | 'C' as u8 => 1,
|
|
|
|
'g' as u8 | 'G' as u8 => 2,
|
|
|
|
't' as u8 | 'T' as u8 => 3,
|
|
|
|
_ => fail!(c.to_str())
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
fn unpack_symbol(c: u8) -> u8 {
|
|
|
|
TABLE[c]
|
|
|
|
}
|
|
|
|
|
|
|
|
fn next_char<'a>(mut buf: &'a [u8]) -> &'a [u8] {
|
|
|
|
loop {
|
|
|
|
buf = slice(buf, 1, buf.len());
|
|
|
|
if buf.len() == 0 {
|
|
|
|
break;
|
|
|
|
}
|
|
|
|
if buf[0] != (' ' as u8) && buf[0] != ('\t' as u8) &&
|
|
|
|
buf[0] != ('\n' as u8) && buf[0] != 0 {
|
|
|
|
break;
|
|
|
|
}
|
|
|
|
}
|
|
|
|
buf
|
|
|
|
}
|
|
|
|
|
|
|
|
#[inline(never)]
|
|
|
|
fn read_stdin() -> ~[u8] {
|
|
|
|
unsafe {
|
|
|
|
let mode = "r";
|
|
|
|
//let stdin = fdopen(STDIN_FILENO as c_int, transmute(&mode[0]));
|
|
|
|
let path = "knucleotide-input.txt";
|
|
|
|
let stdin = fopen(transmute(&path[0]), transmute(&mode[0]));
|
|
|
|
|
|
|
|
let mut st: stat = init();
|
|
|
|
fstat(fileno(stdin), &mut st);
|
|
|
|
let mut buf = vec::from_elem(st.st_size as uint, 0);
|
|
|
|
|
|
|
|
let header = str::byte_slice_no_callback(">THREE");
|
|
|
|
let header = vec::slice(header, 0, 6);
|
|
|
|
|
|
|
|
{
|
|
|
|
let mut window: &mut [u8] = buf;
|
|
|
|
loop {
|
|
|
|
fgets(transmute(&mut window[0]), LINE_LEN as c_int, stdin);
|
|
|
|
|
|
|
|
{
|
|
|
|
if vec::slice(window, 0, 6) == header {
|
|
|
|
break;
|
|
|
|
}
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
while fgets(transmute(&mut window[0]),
|
|
|
|
LINE_LEN as c_int,
|
|
|
|
stdin) != null() {
|
|
|
|
window = vec::mut_slice(window,
|
|
|
|
strlen(transmute(&window[0])) as uint,
|
|
|
|
window.len());
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
buf
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
#[inline(never)]
|
|
|
|
#[fixed_stack_segment]
|
|
|
|
fn generate_frequencies(frequencies: &mut Table,
|
|
|
|
mut input: &[u8],
|
|
|
|
frame: i32) {
|
|
|
|
let mut code = Code(0);
|
2013-05-03 18:25:04 -05:00
|
|
|
|
2013-04-17 20:59:54 -05:00
|
|
|
// Pull first frame.
|
|
|
|
for (frame as uint).times {
|
|
|
|
code = code.push_char(input[0]);
|
|
|
|
input = next_char(input);
|
|
|
|
}
|
|
|
|
frequencies.lookup(code, BumpCallback);
|
|
|
|
|
|
|
|
while input.len() != 0 && input[0] != ('>' as u8) {
|
|
|
|
code = code.rotate(input[0], frame);
|
|
|
|
frequencies.lookup(code, BumpCallback);
|
|
|
|
input = next_char(input);
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
#[inline(never)]
|
|
|
|
#[fixed_stack_segment]
|
|
|
|
fn print_frequencies(frequencies: &Table, frame: i32) {
|
|
|
|
let mut vector = ~[];
|
|
|
|
for frequencies.each |entry| {
|
|
|
|
vector.push((entry.code, entry.count));
|
|
|
|
}
|
|
|
|
quick_sort3(vector);
|
|
|
|
|
|
|
|
let mut total_count = 0;
|
|
|
|
for vector.each |&(_, count)| {
|
|
|
|
total_count += count;
|
|
|
|
}
|
|
|
|
|
|
|
|
for vector.each |&(key, count)| {
|
|
|
|
println(fmt!("%s %.3f",
|
|
|
|
key.unpack(frame),
|
|
|
|
(count as float * 100.0) / (total_count as float)));
|
|
|
|
}
|
|
|
|
}
|
|
|
|
|
|
|
|
fn print_occurrences(frequencies: &mut Table, occurrence: &'static str) {
|
|
|
|
frequencies.lookup(Code::pack(occurrence), PrintCallback(occurrence))
|
|
|
|
}
|
|
|
|
|
|
|
|
#[fixed_stack_segment]
|
|
|
|
fn main() {
|
|
|
|
let input = read_stdin();
|
|
|
|
|
|
|
|
let mut frequencies = ~Table::new();
|
|
|
|
generate_frequencies(frequencies, input, 1);
|
|
|
|
print_frequencies(frequencies, 1);
|
|
|
|
|
|
|
|
*frequencies = Table::new();
|
|
|
|
generate_frequencies(frequencies, input, 2);
|
|
|
|
print_frequencies(frequencies, 2);
|
|
|
|
|
|
|
|
for range(0, 5) |i| {
|
|
|
|
let occurrence = OCCURRENCES[i];
|
|
|
|
*frequencies = Table::new();
|
|
|
|
generate_frequencies(frequencies,
|
|
|
|
input,
|
|
|
|
occurrence.len() as i32);
|
|
|
|
print_occurrences(frequencies, occurrence);
|
|
|
|
}
|
|
|
|
}
|